First asymmetric total synthesis of (+)-sparteine.
نویسندگان
چکیده
[reaction: see text] The total synthesis of (+)-sparteine was accomplished from 2,5-norbornadione in 15 steps and 15.7% overall yield. The key steps were two ring-expansion reactions, one involving an intramolecular Schmidt reaction and one using a novel variant of the photo-Beckmann rearrangement.
منابع مشابه
First asymmetric synthesis of planar chiral [2.2]metacyclophanes.
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ورودعنوان ژورنال:
- Organic letters
دوره 4 15 شماره
صفحات -
تاریخ انتشار 2002